Cimetidine(51481-61-9)
Product Description
● Cimetidine has preventive and protective effects on corrosive gastritis caused by chemical irritation, and also has significant efficacy on stress gastric ulcer and upper gastrointestinal bleeding.
● Cimetidine is a histamine H2 receptor impedant, mainly used to inhibit gastric acid secretion, which can significantly inhibit basal and nocturnal gastric acid secretion, and also inhibit gastric acid secretion caused by histamine, fractional peptide gastrin, insulin and food stimulation, and make it less acidic. Cimetidine has a preventive and protective effect on corrosive gastritis caused by chemical stimulation, and also has significant efficacy on stress gastric ulcer and upper gastrointestinal bleeding.
● Quality Standard: USP
| Item | Standard | Result |
| Appearane | White or almost while Crystalline Powder odourless, bitter taste | Confbnn |
| Identification | ||
| A:(IR) | Conform to USP Cimetidine RS | Conform |
| B:(UV) | Conform lo USP Cimetidine RS | Conform |
| Assay (calculated on the dried basis) | 98.0-102.0% | 99.9% |
| Impurities | ||
| Residue on ignition | NMT 0.2% | Conform |
| Heavy metals | NMT 20ppm | Conform |
| Organic impurities | Any Individual impurity NMT 0.2% | NMT 0.2% |
| Total impurities NMT 1.0% | NMT 1.0% | |
| Melting range or Tempeature | 139-144 °C | 141-143*C |
| Loss on drying | NMT 1.0% | 0.22% |
| Residual solvents (ethanol) | NMT 0.5% | NMT 0.5% |
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