Proteinase K: The "golden partner" for nucleic acid extraction and purification

Proteinase K is a broad-spectrum serine protease derived from Tritirachium album limber and belongs to the subtilisin family. It can efectively hydrolyze proteins, eliminating their interference in experiments such as nucleic acid extraction and purification. Suitable for fields including DNA/RNA extraction, proteomics research, and biopharmaceuticals, it is a commonly used tool enzyme in molecular biology and life science research.

Key Highlights

Outstanding Stability

The test results of three batches showed that proteinase K lyophilized powder and liquid can be stably stored at room temperature for 3 years, maintaining >90% activity.

Excellent guanidine salt tolerance

Compared with Company N and Company R, Hyasen's Proteinase K has comparable tolerance to Guanidine Hydrochloride and Guanidine thiocyanate.

No contaminating enzyme residues

Free of DNase, RNase, and Nickase residues, guaranteeing maximum recovery of intact genomic DNA/RNA from diverse sample types.

Large-Scale Production Capability

Single-batch capacity of 1500L/30KG, ensuring reliable supply and consistent product quality.

DNA Residue Control

HYC113 (for NGS): Nucleic acid residue ≤ 5 pg/mg; Bioburden ≤ 50 CFU/g

HYC114 (for mNGS): No background nucleic acid residues, ideal for nucleic acid extraction in mNGS workflows.

Available Formats

Supplied as lyophilized powder (general or NGS grade) or liquid (general or mNGS grade).

Hyasen Biotech — your trusted partner for high-quality, high-performance reagents that drive innovation in molecular diagnostics and biotechnology !