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RNase A: Precision-Engineered for Molecular Biology Excellence — Your Go-To for RNA Removal & Beyond

2026-01-22

What is RNase A?

RNase A (Ribonuclease A) is an incredibly important and widely used enzyme, whose core function is to catalyze the hydrolysis of RNA (i.e., degradation or digestion). Simply put, RNase A is the "scissors" for RNA — it cleaves long RNA chains into small fragments.

What are the applications of RNase A in molecular biology experiments?

  • Plasmid DNA Preparation

When extracting plasmid DNA from bacteria, a large amount of RNA (e.g., rRNA, tRNA) is co-extracted. RNase A is added to the DNA sample to efficiently degrade these RNA impurities, yielding high-purity plasmid DNA. Without RNA removal, blurred background bands will form in agarose gel electrophoresis, interfering with the observation and analysis of DNA bands.

  • RNA Contamination Removal

In many molecular biology experiments (e.g., PCR, restriction enzyme digestion, sequencing), trace RNA contamination may compromise experimental results. Adding RNase A ensures DNA samples are free of RNA.

Why Hyasen HYC115 RNase A Stands Out:

✅ With an activity of ≥60 Kunitz units/mg.

✅ Versatility Across Salt Conditions

✅ DNase-Free Assurance

✅ Stays stable for 2 years when stored at -25~-15℃.

✅ Supplied in 0.1g, 1g, and 10g sizes to fit labs of all scales.

Ready to elevate your workflows? Explore HYC115 RNase A today and experience the Hyasen Biotech difference.