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Oxytetracycline Hcl( 2058-46-0) Featured Image
  • Oxytetracycline Hcl( 2058-46-0)

Oxytetracycline Hcl( 2058-46-0)


CAS number: 2058-46-0

MF:  C22H25ClN2O9

Product Description

New Description

Product Tags

Product Description

Oxytetracycline is a broad-spectrum tetracycline antibiotic, the second of the group to be discovered.

Oxytetracycline works by interfering with the ability of bacteria to produce essential proteins. Without these proteins, the bacteria cannot grow, multiply and increase in numbers. Oxytetracycline therefore stops the spread of the infection and the remaining bacteria are killed by the immune system or eventually die.

Oxytetracycline is a broad-spectrum antibiotic, active against a wide variety of bacteria. However, some strains of bacteria have developed resistance to this antibiotic, which has reduced its effectiveness for treating some types of infections.

Oxytetracycline is used to treat infections caused by Chlamydia (e.g. the chest infection psittacosis, the eye infection trachoma, and the genital infection urethritis) and infections caused by Mycoplasma organisms (e.g. pneumonia).

Oxytetracycline is also used to treat acne, due to its activity against the bacteria on the skin that influence the development of acne (Cutibacterium acnes). It is used to treat flare-ups of chronic bronchitis, due to its activity against the bacteria usually responsible, Haemophilus influenzae. Oxytetracycline may also be used to treat other rarer infections, such as those caused by a group of micro-organisms called rickettsiae (e.g. Rocky Mountain spotted fever). To make sure the bacteria causing an infection are susceptible to it, a tissue sample is usually taken, for example a swab from the infected area, or a urine or blood sample.

Name of Product:

Oxytetraycline Hcl

Shelf Life:

4 years

Specification:

BP2011

Test Items

Specification

Results of Analysis

Appearance

Yellow crystalline powder

Complies

Solubility

Freely soluble in water, sparingly soluble in ethanol, solutions in water become turbid on standing, owing to the precipitation of Oxytetracycline.

Complies

Identification

According to BP

Complies

Tests

pH

2.3-2.9

2.5

Absorbance

270-290

271

Specific optical rotation

-188° to -200°

-190°

Heavy metals

Not more than 50

Complies

Light absorbing impurities

Absorbance at 430nm shall not be more than 0.50

0.32

Absorbance at 490nm shall not be more than 0.20

0.1

Related substances

content of impurity peak meets the requirements

Complies

Sulphatd ash

Not more than 0.5%

0.09%

Water

Not more than 2.0%

1.2%

HPLC Assay

95.0%-102.0%

96.1%


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