Product Overview
Modified nucleotides are an important part of modern mRNA design. Replacing uridine with a modified form such as pseudouridine is one of the ways that mRNA vaccines and therapeutics are developed, and the quality of the modified nucleotide feeds directly into the yield and purity of the transcript. Pseudo UTP (pseudouridine triphosphate) Sodium Solution serves as a key modified nucleotide component for the production of modified mRNA, supporting the development and manufacturing of next-generation mRNA vaccines, gene therapies, and nucleic acid-based medicines. It is a high-purity nucleotide substrate designed for in vitro transcription (IVT), mRNA synthesis, and mRNA-based therapeutic development.
The product is manufactured in a GMP-compliant production environment with a completely animal-origin-free process, and it meets stringent quality requirements for applications from preclinical research to commercial-scale mRNA manufacturing. Its purity is >99%, and stringent impurity control and ultra-low metal residue levels support high-quality mRNA production. Comprehensive quality management gives strong batch-to-batch consistency, and DMF filing support is available. Pseudo UTP Sodium Solution is part of a complete nucleotide product portfolio, and customized specifications can be discussed to meet different process requirements. The product should be transported below 0°C and stored at -25°C to -15°C to maintain stability.
Product Features
- Key modified nucleotide for modified mRNA: Pseudo UTP serves as the modified nucleotide component for IVT production of modified mRNA, supporting mRNA vaccines, gene therapies, and nucleic acid-based medicines across the development pipeline.
- GMP-compliant, animal-origin-free manufacturing with DMF support: The product is made in a GMP-compliant environment with comprehensive quality management, a completely animal-origin-free process, and strong batch-to-batch consistency. DMF filing support is available.
- High purity with low impurities and ultra-low metal residues: Purity is above 99%, with strict quality control, stringent impurity control, and ultra-low metal residue levels to support consistent IVT and mRNA synthesis performance. Customized specifications are available on request.
FAQ
Q1: What is Pseudo UTP Sodium Solution used for?
It is mainly used as a modified nucleotide substrate for in vitro transcription (IVT) and modified mRNA synthesis, in mRNA vaccine development and manufacturing, gene therapy drug R&D, and nucleic acid-based therapeutic development, from preclinical research to GMP-scale commercial production.
Q2: Is it suitable for GMP manufacturing, and does the process use animal-derived materials?
The product is manufactured in a GMP-compliant production environment with strict quality control and supports applications from preclinical development to GMP-scale manufacturing. The manufacturing process is completely animal-origin-free, and DMF filing support is available. Please contact us to discuss the documentation you need.
Q3: How should Pseudo UTP Sodium Solution be stored and transported?
It should be transported below 0°C and stored at -25°C to -15°C to maintain stability. Customized specifications and supply solutions are available according to your requirements.
