Riboflavin /Vitamin B2(83-88-5)
Riboflavin, also known as vitamin B2, is a vitamin found in food and sold as a dietary supplement. It is essential to the formation of two major coenzymes, flavin mononucleotide and flavin adenine dinucleotide. These coenzymes are involved in energy metabolism, cellular respiration, and antibody production, as well as normal growth and development. The coenzymes are also required for the metabolism of niacin, vitamin B6, and folate. Riboflavin is prescribed to treat corneal thinning, and taken orally, may reduce the incidence of migraine headaches in adults.
Riboflavin deficiency is rare and is usually accompanied by deficiencies of other vitamins and nutrients. It may be prevented or treated by oral supplements or by injections. As a water-soluble vitamin, any riboflavin consumed in excess of nutritional requirements is not stored; it is either not absorbed or is absorbed and quickly excreted in urine, causing the urine to have a bright yellow tint. Natural sources of riboflavin include meat, fish and fowl, eggs, dairy products, green vegetables, mushrooms, and almonds. Some countries require its addition to grains.
energy metabolism, cell respiration, antibody production, growth and development.Riboflavin is essential for the metabolism of carbohydrates, protein and fats.FAD contributes to conversion of tryptophan to niacin (vitamin B3) and the conversion of vitamin B6 to the coenzyme pyridoxal 5'-phosphate requires FMN. Riboflavin is involved in maintaining normal circulating levels of homocysteine; in riboflavin deficiency, homocysteine levels increase, elevating the risk of cardiovascular diseases.
|Appearance||Orange Yellow Crystalline Powder||Conform|
|Acidity or Alkalinity||Check the color of the test solution
After adding the respective solutions
|Lumiflavin||Absorbance of the filtrate at 440nm
Does not exceed 0.025(USP);
|Absorbance||0.31 – 0.33 A375nm/A267nm
0.36 – 0.39 A444nm/A267nm
|Partical Size||100% pass 60 mesh||Conform|
|Loss on Drying||≤1.5%||0.8%|
|Residue on Ignition||≤0.03%(USP)||0.1%|
|Organic Volatile Impurities||Method IV<467>(USP)||Conform|
|Assay(on dried basis)||98.0% - 102.0%(USP)||99.85%|