Product Overview
UTP is the uridine-containing ribonucleotide substrate in IVT reactions, incorporated opposite adenine in the DNA template. Every nucleotide in the reaction affects the yield and purity of the mRNA, and for mRNA vaccines, gene therapy products, and other nucleic acid-based therapeutics, the raw material also has to meet the documentation and consistency expectations of regulated manufacturing. UTP Sodium Solution is a high-purity nucleotide substrate manufactured in a GMP-compliant production environment, with a completely animal-origin-free process throughout the entire workflow. It is designed for IVT, mRNA synthesis, nucleic acid drug development, and large-scale mRNA manufacturing, and it supports the development and production of mRNA vaccines, gene therapy products, and other nucleic acid-based therapeutics from early-stage research and preclinical studies to commercial manufacturing. Advanced purification processes give a purity of >99%, with low impurity levels and ultra-low metal residue content to support sensitive IVT and mRNA production workflows. Comprehensive quality control systems support excellent batch-to-batch consistency and reliable supply for commercial applications, and DMF filing support is available. UTP Sodium Solution is part of a complete nucleotide product portfolio, and customized specifications and requirements can be discussed to meet different customer needs. The product should be transported frozen below 0°C and stored at -25°C to -15°C to maintain stability and quality.
Product Features
- High purity and reliable performance: Advanced purification gives purity above 99%, low impurity levels, and ultra-low metal residue content, supporting sensitive IVT and mRNA production workflows.
- GMP-compliant manufacturing with DMF support: The product is produced under GMP-compliant conditions with comprehensive quality control systems, giving excellent batch-to-batch consistency and reliable supply for commercial applications. DMF filing support is available.
- Animal-origin-free process and flexible supply: The entire manufacturing workflow is free of animal-derived materials, and a complete nucleotide product portfolio is available with customized specifications to meet diverse customer needs.
FAQ
Q1: What is UTP Sodium Solution used for?
It is primarily used as a nucleotide substrate for in vitro transcription (IVT) and mRNA synthesis, in mRNA vaccine development and manufacturing, gene therapy drug development, nucleic acid drug R&D, and GMP-scale mRNA production, from preclinical research to commercial-scale manufacturing.
Q2: Is it suitable for GMP manufacturing, and does the process use animal-derived materials?
The product is manufactured in a GMP-compliant production environment with strict quality control systems and supports applications from preclinical development to commercial manufacturing. The entire manufacturing workflow is animal-origin-free, and DMF filing support is available. Please contact us to discuss the documentation you need.
Q3: How should UTP Sodium Solution be stored and transported?
It should be transported frozen, below 0°C, and stored at -25°C to -15°C to maintain stability and quality. Customized specifications and solutions are available according to your application needs.
