Proteinase K ( Lyophilized powder for NGS)

NGS Protease K is a serine protease with high enzyme activity and wide substrate specificity. The enzyme preferentially decomposes ester bonds and peptide bonds adjacent to the  C-terminal of hydrophobic amino acids, sulfur-containing amino acids and aromatic amino acids. So, it is often used to degrade proteins into short peptides. NGS Protease K is a typical serine protease with the Asp39-His69-Ser224 catalytic triad which is unique to serine proteases, and the catalytic center is surrounded by tow Ca 2+ binding sites for stabilization, maintaining high enzyme activity under a wider range of conditions.